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Correct folding of proteins is essential for maintaining a functional living cell. Misfolding and aggregation of proteins, where non-native intermolecular interactions form large and highly ordered amyloid aggregates with low free energy, is hence associated with multiple diseases. One example is Al...
50 Page(s) / 13750 words USD 40.00Admission
Liposomes are widely used in drug delivery to improve drug efficacy and to reduce side effects. For liposome-encapsulated drugs to become bioavailable and provide a therapeutic effect they must be released, which typically is a slow process that primarily relies on passive diffusion, liposome ruptur...
50 Page(s) / 13750 words USD 40.00Admission
Amyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed ...
50 Page(s) / 13750 words USD 40.00Admission
Biophysical chemistry deals with the structural behavior, properties and molecular function of biological macromolecules. A long-standing challenge is here to establish how these macromolecular features change upon transfer from simplified conditions in vitro to the crowded and molecularly complex e...
50 Page(s) / 13750 words USD 40.00Admission
The overall aim of this thesis is to investigate how teachers talk about genetics in actual classroom situations. An understanding of how language is used in action can give detailed information about how the subject matter is presented to the students as well as insights in linguistic challenges. F...
50 Page(s) / 13750 words USD 40.00Admission
High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex mi...
50 Page(s) / 13750 words USD 40.00Admission
Chemical bonding is a vast subject, rich in abstract concepts and advanced and less-advanced explanatory models that the learner has to master. In this context, the teaching of chemical bonding at the secondary school level is extremely important, as it has the potential to increase or hinder studen...
50 Page(s) / 13750 words USD 40.00Admission
The importance of an education that empowers students to engage with real societal problems to promote a sustainable future is widely acknowledged. However, the organisational characteristics of schools that facilitate such education for sustainable development (ESD) have received little attention. ...
50 Page(s) / 13750 words USD 30.00Admission
In this Licentiate thesis I examine the system of physics teacher education. Physics teacher education is important because it is one of the main ways to influence how physics is taught in schools. By extension, physics teacher education has the potential to affect both who chooses to pursue physics...
50 Page(s) / 13750 words USD 30.00Admission
The interest in lignocellulose as a sustainable resource for energy and materials has fueled research on biotechnology applications in tree breeding to improve biomass production and wood properties. An important aspect of this research is the basic understanding of gene function in wood formation, ...
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